Lion's Mane Mushroom Research

Teelixir's evidence-based guide to Hericium erinaceus — the only mushroom shown to stimulate Nerve Growth Factor (NGF) in human tissue. Our research library draws on 571+ published studies, including 28 human clinical trials, to give you an honest picture of what lion's mane can and cannot do.

Lion's Mane

Apr 26, 2026

How Lion's Mane Works: The NGF Pathway and What It Actually Does in the Brain

How does lion's mane mushroom actually work in the brain? A mechanism-first review of hericenones, erinacines, NGF stimulation, and what dual-extraction means for bioactive availability.

Apr 09, 2026

Lion's Mane and Ashwagandha: The Build-and-Protect Stack

Lion's mane and ashwagandha target completely different biological systems — one sharpens cognition, the other resets the stress response. Here is what the evidence says about using them together.

Teelixir Lion s Mane Mushroom Extract — adhd focus

Apr 09, 2026

Lion's Mane for ADHD and Focus: What the Research Actually Shows

By Peter Orpen — Co-Owner, Teelixir Published: 24 March 2026Updated: 27 March 2026 In This Guide ADHD is a dopamine problem. At least, that's the simplified version you hear everywhere. In This Article The Honest Truth: No ADHD-Specific Trials Exist...

Lion's mane mushroom Hericium erinaceus growing on ancient wood, white cascading spines in natural light

Apr 09, 2026

Lion's Mane for Brain Fog: Does It Actually Work?

7 human RCTs reviewed. Studies suggest lion’s mane may help with mental clarity and processing speed. Practical doses, honest limitations, timelines.

Lion's Mane mushroom powder in a shaker bottle against a terracotta background with running shoes, for Teelixir's athlete performance guide

Apr 09, 2026

Lion's Mane for Athletes: Performance, Recovery, and Honest Expectations

Can lion's mane improve athletic performance? Anti-fatigue animal data, zero human exercise trials, but promising cognitive performance evidence for mental athletics.

Lion's mane mushroom with tea on garden table in afternoon light

Apr 09, 2026

Lion's Mane for Seniors: The Strongest Human Evidence

Seniors have the most clinical evidence for lion's mane. Three RCTs show improved cognition in older adults with mild impairment. Doses, limitations, and practical guidance.